CMS launched the $50 billion Rural Health Transformation Program, the largest federal investment ever in rural health care. Created under the Working Families Tax Cuts Act, the five-year program will modernize rural health systems, expand access to high-quality care, build workforce capacity, and foster innovative models including telehealth. States have until November 5, 2025 to apply for this one-time funding opportunity, with awards announced December 31, 2025 and funding beginning in FY 2026.